A uniquely leptin sensitive hypothalamic neuron population limits hyperphagia and weight gain in diet-induced obesity
Dylan M. Belmont-Rausch, Benedicte Schultz Kapel, Abigail J. Tomlinson…·Tune H. Pers
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University of CopenhagenORCID 0000-0003-2456-9667Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Dylan M. Belmont-Rausch, Benedicte Schultz Kapel, Abigail J. Tomlinson…·Tune H. Pers
Valdemar Brimnes Ingemann Johansen, Jens Teglgaard Lund, María J Romero-Lado…·Christoffer Clemmensen
This study identifies chondroitin sulfate as a potential therapeutic target for type 2 diabetes through genetic and preclinical evidence showing its effects on glycemic control and insulin action.
Ye Cao, Kyle C. Feola, Wenke Jonas…·Maximilian Kleinert
This study shows dietary medium-chain fatty acids provide metabolic benefits without requiring hepatic ketogenesis.
Nathalie Krauth, Lara Kristin Sach, Giacomo Sitzia…·Ole Kiehn
This paper identifies a hypothalamus-brainstem circuit that prioritizes safety over essential needs by modulating locomotion behavior.
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles
This study examines sex-specific metabolic effects of FGF21 deficiency and glucagon analog treatment in female mice, revealing exacerbated obesity and altered glucose tolerance in females.
Pablo Ranea‐Robles, Camilla Lund, Charlotte Svendsen…·Christoffer Clemmensen
This study shows overfeeding in mice does not increase energy expenditure or excretion, and weight gain is mainly countered by reduced food intake.