Author

Yaoyin Li

University of Notre DameORCID 0000-0003-2475-5355Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Xin LüiD· 2 shared Adrian ChaoiD· 1 shared Dailin GaniD· 1 shared Éva SzegezdiiD· 1 shared Guoqiang LiuiD· 1 shared Jianping HeiD· 1 shared Jiling WeniD· 1 shared Junling Zhao· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Xin LüORCID

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2 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 1, 2026

Synthetic essentiality of TRAIL/TNFSF10 in VHL-deficient renal cell carcinoma

Xuechun Wang, Yujing Qin, Loan Duong…·Éva Szegezdi

This study identifies TRAIL as a synthetic essentiality in VHL-deficient ccRCC, showing its regulation by HIF2 and its role in cell proliferation through the p38 MAPK pathway, suggesting a combination therapy strategy.

DOI 10.1073/pnas.2535452123

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintOct 21, 2025

An oncogenotype-immunophenotype paradigm governing the myeloid landscape in genetically engineered mouse models of prostate cancer

Yuting Zhang, Yaoyin Li, Dailin Gan…·Xin Lü

The paper identifies a Smad4-loss-driven neutrophil-enriched subtype in prostate cancer models and shows that targeting epigenetic enzymes can suppress tumor growth.

1 citation

mousebulk RNA-seq

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