Author

Guoqiang Liu

University of Notre DameORCID 0000-0002-8212-6875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Loan DuongiD· 2 shared Xin LüiD· 2 shared Adrian ChaoiD· 1 shared Ariana ArceiD· 1 shared Éva SzegezdiiD· 1 shared Jianping HeiD· 1 shared Jiling WeniD· 1 shared Jing Hui YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Loan DuongORCID

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2 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 1, 2026

Synthetic essentiality of TRAIL/TNFSF10 in VHL-deficient renal cell carcinoma

Xuechun Wang, Yujing Qin, Loan Duong…·Éva Szegezdi

This study identifies TRAIL as a synthetic essentiality in VHL-deficient ccRCC, showing its regulation by HIF2 and its role in cell proliferation through the p38 MAPK pathway, suggesting a combination therapy strategy.

DOI 10.1073/pnas.2535452123

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 18, 2025

CDH3 as a Novel Therapeutic Target in Basal-like Double-Negative Prostate Cancer

Guoqiang Liu, Shiyu Wang, Loan Duong…·Xin Lü

This study identifies CDH3 as a key driver of basal-like prostate cancer and shows that CDH3-targeted therapies like ADCs and CAR T cells are effective in preclinical models.

DOI 10.1101/2025.11.18.689150

mousebulk RNA-seq

𝕏 PostBluesky