Frank L.H. Menke

This study investigates the oligomerization and activation mechanism of the RPS4-RRS1 immune receptor complex in Arabidopsis, showing that effector recognition triggers conformational changes that enable NADase activity.

The paper maps dynamic septin interactions in the rice blast fungus during infection, revealing roles beyond cytoskeletal organization in plant invasion.

This study determines the structural basis of broad recognition by the Arabidopsis NLR WRR4A, revealing a shape-based mechanism that enables recognition of diverse effectors with similar three-dimensional architectures.

The paper identifies a phosphorelay circuit that drives extracellular alkalinization in plant receptor kinase signaling, essential for immune responses.

This study identifies Pwl2 as a virulence factor in the rice blast fungus that suppresses host immunity by altering the localization of HIPP43.

The paper identifies a ubiquitination-deubiquitination cycle regulating the stability and function of the paired NLR receptor complex RRS1/RPS4 in Arabidopsis.

The paper identifies a toggle-switch mechanism in the ERECTA receptor that prevents inappropriate signaling by autoinhibition and rapid degradation after activation.

The paper investigates the neofunctionalization of a Poales-specific EXO70 clade, showing HvEXO70FX12 lost exocyst complex association and may play a role in immunity.

The paper identifies QSK1 as a novel negative regulator of PRR-RBOHD complex and shows it is targeted by the bacterial effector HopF2Pto to suppress plant immunity.