Enoch Lok Him Yuen

A helper NLR monitors catalytic perturbation of a vesicle trafficking regulator targeted by pathogen effectors

The paper shows that the helper NLR NRC4 detects effector-induced changes in TOPGAP activity, leading to immune activation.

A helper NLR channels organellar calcium to trigger plant immunity

This study identifies NRG1 as a plant NLR receptor that targets chloroplasts to trigger immunity by channeling stromal calcium into the cytosol, revealing a novel mechanism for organelle-specific immune signaling.

A broad-host-range Rhizobium rhizogenes strain enables transient expression across diverse crops and establishes functional assays in faba bean

View Tomo: Context-aware targeting and analysis in electron cryo-tomography

View Tomo improves cryoET by enabling 3D analysis and targeting through low-dose, rapid tomogram acquisition and automated processing.

On-lamella super-resolution cryo-CLEM for cryo-ET enabled by vacuum-free ultra-stable cryogenic fluorescence microscopy

This paper introduces VULCROM, a vacuum-free cryogenic fluorescence microscope that enables high-resolution cryo-SR-CLEM and detailed single-molecule studies in vitrified specimens.

A hydrophobic core in the coiled-coil domain is essential for NRC resistosome function

The study identifies a hydrophobic core in the coiled-coil domain of NRCs that is essential for their function in immunity.

A specialized ARGONAUTE enables trans-species RNA interference in plant immunity

This study identifies AGO10 as a key player in trans-species RNA interference in plant immunity, showing its role in pathogen gene silencing and immune response.

An effector from the potato late blight pathogen bridges ENTH-domain protein TOL9a to an activated helper NLR to suppress immunity

This paper identifies an effector from Phytophthora infestans that bridges NbTOL9a to an activated NLR to suppress immunity, revealing a novel structural and functional mechanism.

Single-cell-resolved calcium and organelle dynamics in resistosome-mediated cell death

The paper visualizes calcium signaling and organelle dynamics during resistosome-mediated cell death in plants, revealing a sequential cascade of subcellular events.