Author

Jacob R. Mann

University of PittsburghORCID 0000-0003-2553-6015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alessandra ChesiiD· 1 shared Amanda M. GleixneriD· 1 shared Anastasia C. MurthyiD· 1 shared Ashleigh SmirnoviD· 1 shared Bede PortziD· 1 shared Bo Lim LeeiD· 1 shared Carolann L. EspyiD· 1 shared Christopher J. DonnellyiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Alessandra ChesiORCID

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1 paper

Recent·Most cited

BiochemistryMolecular CellPeer-reviewedJan 1, 2026

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains

Lin Guo, Jacob R. Mann, Jocelyn C. Mauna…·James Shorter

The paper identifies short RNAs that prevent and reverse pathological fibrillization of RNA-binding proteins like FUS and TDP-43, showing therapeutic potential for ALS/FTD.

25 citationstop 1%

humanbulk RNA-seq

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