Carmen Marino

This study uses NMR-metabolomics to show CHF6467 mitigates Aβ(1-42)-induced metabolic changes in SH-SY5Y cells by promoting phospholipid precursors, reducing glutamate excitotoxicity, and restoring energy metabolism.

This study uses NMR-pharmacometabolomics to investigate how nicotine mitigates amyloid toxicity in SH-SY5Y cells, revealing its role in restoring metabolic imbalances linked to Alzheimer's disease.

This study shows that RNase H1 reduces DNA damage and improves SMA-like symptoms in a Drosophila model by resolving RNA:DNA hybrids caused by SMN deficiency.