Author

Grazia Daniela Raffa

Sapienza University of RomeORCID 0000-0002-5072-5240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Organism:C. elegans· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Livia Scatolini· 3 shared Maurizio GattiiD· 3 shared Paolo MaccalliniiD· 3 shared Stefano CacchioneiD· 3 shared Alessio ColantoniiD· 2 shared Cristiano De PittàiD· 2 shared Francesca Bavasso· 2 shared Gabriele Proietti· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Livia Scatolini

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RNase H1 counteracts DNA damage and ameliorates SMN-dependent phenotypes in a Drosophila model of Spinal Muscular Atrophy

Livia Scatolini, Lucia Graziadio, Damiano Guerrini, Paolo Maccallini, Carmen Marino, Raffaella di Vito, Amber Hassan, Manuela Grimaldi, Marco Fidaleo, Roozbeh Dehghannasiri, Gabriele Proietti, Roberto Piergentili, Erica Salvati, Stefano Cacchione, Cristiano De Pittà, , Grazia Daniela Raffa

This study shows that RNase H1 reduces DNA damage and improves SMA-like symptoms in a Drosophila model by resolving RNA:DNA hybrids caused by SMN deficiency.

bioRxiv · Apr 17, 2025 · PreprintGenetics

TGS1 controls snRNA 3' end processing, prevents neurodegeneration and ameliorates SMN-dependent neurological phenotypes in vivo

Lü Chen, Caitlin M. Roake, Paolo Maccallini, Francesca Bavasso, Roozbeh Dehghannasiri, Pamela Santonicola, Natalia Mendoza-Ferreira, Livia Scatolini, Ludovico Rizzuti, Alessandro Esposito, Ivan Gallotta, Sofia Francia, Stefano Cacchione, Alessandra Galati, Valeria Palumbo, , Grazia Daniela Raffa

This study shows TGS1 is essential for snRNA 3' end processing and its loss causes neurodegeneration, which can be mitigated by human TGS1 expression in model organisms.

bioRxiv · Oct 27, 2020 · PreprintGenetics

Intimate functional interactions between TGS1 and the Smn complex revealed by an analysis of the Drosophila eye development

Paolo Maccallini, Francesca Bavasso, Livia Scatolini, Elisabetta Bucciarelli, Gemma Noviello, Veronica Lisi, Valeria Palumbo, Simone D’Angeli, Stefano Cacchione, Giovanni Cenci, Laura Ciapponi, James G. Wakefield, Maurizio Gatti, Grazia Daniela Raffa

This study identifies functional interactions between TGS1 and the Smn complex in Drosophila eye development, showing their roles in retinal progenitor cell viability and eye size.

PLoS Genetics · May 26, 2020Peer-reviewedGenetics