Author

Neesha Kara

Babraham InstituteORCID 0000-0003-2646-1473Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:DNA methylation· 1 Research Focus:genome assembly· 1 Organism:human· 1 Organism:yeast· 1

Frequent Co-Authors

Jonathan M. HouseleyiD· 2 shared Peter J. Rugg‐GunniD· 2 shared Aled ParryiD· 1 shared Alex J. WhaleiD· 1 shared Felix KruegeriD· 1 shared Helen M.R. RobinsoniD· 1 shared Jhanavi Srinivasan· 1 shared Laura BigginsiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Jonathan M. HouseleyORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJun 9, 2025

TrAEL-seq captures DNA replication dynamics in mammalian cells

Neesha Kara, Laura Biggins, Vera V. Grinkevich…·Jonathan M. Houseley

TrAEL-seq is a method for profiling DNA replication dynamics in mammalian cells without requiring synchronization or drugs, showing replication fork speed and initiation zone effects.

1 citation

humanmouse

𝕏 PostBluesky

Molecular BiologyPLoS BiologyPeer-reviewedMar 24, 2021

Genome-wide analysis of DNA replication and DNA double strand breaks by TrAEL-seq

Neesha Kara, Felix Krueger, Peter J. Rugg‐Gunn, Jonathan M. Houseley

This paper introduces TrAEL-seq, a method to detect DNA replication fork stalling and double strand breaks with high resolution, and demonstrates its application in yeast and mammalian cells.

55 citations

yeastmouse

𝕏 PostBluesky