PhysiologybioRxivPreprint
Evolutionarily conserved temperature dependency leads to loss of protein O-GlcNAc in mammalian hypothermia
Divya Upadhyay, Christa Kietz, Nasrin Sultana…·Jukka Kallijärvi
This study identifies temperature as an evolutionarily conserved regulator of O-GlcNAcylation, showing that hypothermia reduces O-GlcNAc levels across species.
DOI 10.1101/2025.07.08.660373