Jukka Kallijärvi

This study uses gene replacement in a mouse model of GRACILE syndrome to show improved energy metabolism and doubled survival through liver-specific correction of a mitochondrial complex III deficiency.

This study evaluates variability in kidney organoid structure development across different culture approaches and iPSC lines using high-throughput methods.

This study identifies temperature as an evolutionarily conserved regulator of O-GlcNAcylation, showing that hypothermia reduces O-GlcNAc levels across species.

This study shows that restoring mitochondrial complex III function in the liver of CIII-deficient mice prevents hypothermia and improves survival by enabling normal thermoregulation.

The paper develops a chromatography-free assay to quantify all 12 canonical ribonucleotides in biological samples using real-time fluorogenic detection during in vitro transcription.

The paper introduces a sensitive microplate assay for quantifying dNTPs using long synthetic oligonucleotides, EvaGreen dye, and inhibitor-resistant DNA polymerase, enabling reliable measurement in mouse tissues.