Cancer BiologybioRxivPreprint
MLL3 adaptor function, not methyltransferase catalytic activity, is essential for breast tumor suppression
Kenta Nishitani, Jihong Cui, Marcelo Coutinho de Miranda…·Wenjun Guo
This study shows that MLL3's tumor suppressor role in breast cancer depends on its adaptor function, not its catalytic activity.