Author

Wenjun Guo

Albert Einstein College of MedicineORCID 0000-0002-6960-7957Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Burcu Karadal-FerrenaiD· 1 shared Camille L. DuraniD· 1 shared David R. EntenbergiD· 1 shared Gregoire S. LauvauiD· 1 shared Guojia XieiD· 1 shared Jihong CuiiD· 1 shared Jiufeng LiiD· 1 shared John S. CondeelisiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Burcu Karadal-FerrenaORCID

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3 papers

Recent·Most cited

MLL3 adaptor function, not methyltransferase catalytic activity, is essential for breast tumor suppression

Kenta Nishitani, Jihong Cui, Marcelo Coutinho de Miranda, Guojia Xie, Nicole Couturier, Yuta Matsuno, Masako Suzuki, Gregoire S. Lauvau, Kai Ge, Wenjun Guo

This study shows that MLL3's tumor suppressor role in breast cancer depends on its adaptor function, not its catalytic activity.

bioRxiv · Jun 8, 2026 · PreprintCancer Biology

Metastatic dissemination of breast cancer stem cells requires MenaINV for lung extravasation but not survival

Mohd Nauman, Yookyung Jung, Burcu Karadal-Ferrena, Suryansh Shukla, Camille L. Duran, Jiufeng Li, Prachiben P. Patel, Madeline Friedman, Nicole D. Barth, Robert J. Eddy, Wenjun Guo, John S. Condeelis, David R. Entenberg, Maja H. Oktay

This study identifies MenaINV as essential for breast cancer stem cell extravasation but not survival, revealing distinct pathways for metastatic dominance.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology

Loss of tumor suppressor p53 upregulates stem cell factor SOX9 via Notch signaling

Rahul Sanawar, Wenjun Guo

This study shows that p53 loss in basal-like breast cancer upregulates SOX9 through Notch signaling, promoting de-differentiation of luminal cells.

bioRxiv · May 27, 2025 · PreprintCancer Biology