Author

Alexander T. Lessenger

Stanford UniversityORCID 0000-0003-2693-1498Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1

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Jan Marcel SkotheimiD· 1 shared Jessica L. FeldmaniD· 1 shared Matthew P. SwafferiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperCell Biology

Jan Marcel SkotheimORCID

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1 paper

Recent·Most cited

Cell BiologyThe Journal of Cell BiologyPeer-reviewedNov 20, 2024

Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output

Alexander T. Lessenger, Jan Marcel Skotheim, Matthew P. Swaffer, Jessica L. Feldman

The paper shows that polyploidy in C. elegans intestine increases transcriptional output and supports biosynthesis by compensating for mRNA dilution through increased RNA Polymerase II loading.

14 citations

C. elegansexperimental assay

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