Kin Kui Lai

This study shows that IFITM1 and IFITM3 work together to block virus entry in endolysosomes, with IFITM3 promoting IFITM1 localization to these compartments.

The paper investigates how mutations in SARS-CoV-2 N protein affect RNP formation and stability, finding convergent evolution and enhanced RNP assembly in Omicron variants.

This study shows that HIV-1 Nef counteracts the antiviral effects of IFITM3 in interferon-treated cells by reducing its cell surface levels and impairing its function.

The paper identifies alternative splicing of IFITM genes in Chinese horseshoe bats, producing two isoforms with differential antiviral activities against influenza and coronaviruses.

This study shows that IP6 and IP5 are essential for MLV replication by stabilizing viral cores and enhancing reverse transcription, unlike HIV-1 which does not require them.