Author

Avery M. Runyan

Columbia University Irving Medical CenterORCID 0000-0003-2710-6334Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Helen Y. Figueroa· 3 shared Natura MyekuiD· 3 shared Eric J. Sydney· 2 shared Malavika Srikanth· 2 shared Mu YangiD· 2 shared Shan JiangiD· 2 shared Ari W. SchaleriD· 1 shared Daniella LormaniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Helen Y. Figueroa

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 20, 2026

Immunoproteasome Deficiency Impairs Microglial Clearance and Worsens Tau and Amyloid Pathology

Malavika Srikanth, Shan Jiang, Steven M. Wellman…·Natura Myeku

This study shows that immunoproteasome deficiency in mice worsens tau and amyloid pathology by impairing microglial clearance.

DOI 10.64898/2026.07.14.738427

mouseproteomics

𝕏 PostBluesky

NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewedApr 4, 2024

5-HT4 receptor agonists treatment reduces tau pathology and behavioral deficit in the PS19 mouse model of tauopathy

Shan Jiang, Eric J. Sydney, Avery M. Runyan…·Natura Myeku

This study shows that 5-HT4 receptor agonists reduce tau pathology and improve cognitive function in PS19 mice with tauopathy.

14 citations

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 21, 2020

GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

Ari W. Schaler, Avery M. Runyan, Stephanie L. Fowler…·Natura Myeku

This study shows that targeting GPCRs to enhance synaptic proteasome activity reduces tau accumulation and cognitive decline in a mouse model of Alzheimer's disease.

2 citations

mouseexperimental assay

𝕏 PostBluesky