Ari W. Schaler

This study shows that microglial mitochondria change with brain region, aging, and inflammation, affecting gene expression and morphology.

The paper identifies tau filaments within extracellular vesicles from Alzheimer's disease patients using mass spectrometry and cryo-electron microscopy.

The paper shows that microglia in specific brain regions exhibit premature aging-related inflammation in middle age, which may affect nearby neurons.

This study shows that targeting GPCRs to enhance synaptic proteasome activity reduces tau accumulation and cognitive decline in a mouse model of Alzheimer's disease.

This study shows that reducing luteinizing hormone or increasing estradiol can reverse memory loss in a schizophrenia model, with hippocampal GABA levels playing a key role.