Author

Shyam S. Ramachandran

Sanofi (United States)ORCID 0000-0003-2716-4251Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:non-human primate· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Bradford M. ElmeriD· 2 shared Christian MuelleriD· 2 shared Ann Byrne· 1 shared Bailin Zhang· 1 shared Can KayatekiniD· 1 shared Chinaza Lilian DibiaiD· 1 shared Dhiman Ghosh· 1 shared Erik Wischhof· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Bradford M. ElmerORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 17, 2025

AAV gene therapy for GBA-PD and Gaucher Disease

Swathi Ayloo, Jae Cheon Ryu, Shih-Ching Chou…·Shyam S. Ramachandran

This paper describes an AAV-mediated gene therapy strategy for GBA1-PD and Gaucher Disease, demonstrating robust GCase replenishment and cross-correction in preclinical models.

DOI 10.1101/2025.06.17.660133

humanmouse

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NeurosciencebioRxivPreprintFeb 9, 2024

Focused ultrasound increases gene delivery to deep brain structure following the administration of a recombinant adeno-associated virus in the cerebrospinal fluid

Rikke Hahn Kofoed, Kate Noseworthy, Kathleen Wu…·Isabelle Aubert

This study shows focused ultrasound enhances gene delivery to deep brain structures when recombinant adeno-associated virus is administered in the cerebrospinal fluid.

1 citation

humannon-human primate

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