Author

Bailin Zhang

Exploratory Biomarkers, Translational Medicine Unit, Sanofi, Cambridge, MA, USA.;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Lilu Guo· 2 shared Alan GuoiD· 1 shared Ann Byrne· 1 shared Anna Blazier· 1 shared Biljana Djukic· 1 shared Bo Yang· 1 shared Bradford M. ElmeriD· 1 shared Can KayatekiniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Lilu Guo

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Author profile →

3 papers

Recent·Most cited

CD40 ligand and IFN-γ induce proinflammatory activity and microglia-mediated neurodegeneration in human stem cell models

Timothy Hammond, Gregory S. Wirak, Sean K. Ryan, Anna Blazier, Dongyu Liu, Ivan Nyarko-Danquah, Michael LaMorte, Shameer Khader, Jose Vela, Bo Yang, Hendrik Wesseling, Bailin Zhang, Frank Rapaport, Roopali Gandhi, Biljana Djukic, Dimitry Ofengeim

This study shows CD40L and IFN-γ induce inflammation and neurodegeneration in human stem cell-derived microglia, suggesting CD40L blockade as a potential MS therapy.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

RNA Editing of DEGS1 Links Genetic Risk to Ceramide Dysregulation and Astrocyte Toxicity in ALS

Alan Guo, Samuel Lessard, Lilu Guo, Melody Li, Disha Sood, Rachel Passaro, Jeremy Huang, Clément Chatelain, Emanuele de Rinaldis, Khader Shameer, Bailin Zhang, James C. Dodge, Steven Rodriguez

bioRxiv · Sep 22, 2026 · PreprintNeuroscience

AAV gene therapy for GBA-PD and Gaucher Disease

Swathi Ayloo, Jae Cheon Ryu, Shih-Ching Chou, Lydia Blatnik, Erik Wischhof, Jie Bu, Lilu Guo, Mahmud Hossain, Dhiman Ghosh, William McCarty, Ann Byrne, Lilly Chai, J T Clarke, Can Kayatekin, Bailin Zhang, , Shyam S. Ramachandran

This paper describes an AAV-mediated gene therapy strategy for GBA1-PD and Gaucher Disease, demonstrating robust GCase replenishment and cross-correction in preclinical models.

bioRxiv · Jun 17, 2025 · PreprintNeuroscience