Author

Ann Byrne

Sanofi (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Can KayatekiniD· 2 shared Lilly Chai· 2 shared S. Pablo SardiiD· 2 shared Bailin Zhang· 1 shared Beril Kiragasi· 1 shared Bradford M. ElmeriD· 1 shared Christian MuelleriD· 1 shared Dhiman Ghosh· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Can KayatekinORCID

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Author profile →

2 papers

Recent·Most cited

AAV gene therapy for GBA-PD and Gaucher Disease

Swathi Ayloo, Jae Cheon Ryu, Shih-Ching Chou, Lydia Blatnik, Erik Wischhof, Jie Bu, Lilu Guo, Mahmud Hossain, Dhiman Ghosh, William McCarty, Ann Byrne, Lilly Chai, J T Clarke, Can Kayatekin, Bailin Zhang, , Shyam S. Ramachandran

This paper describes an AAV-mediated gene therapy strategy for GBA1-PD and Gaucher Disease, demonstrating robust GCase replenishment and cross-correction in preclinical models.

bioRxiv · Jun 17, 2025 · PreprintNeuroscience

Network Analysis and Human Single Cell Brain Transcriptomics Reveal Novel Aspects of Alpha-Synuclein (SNCA) Biology

Erin A. Teeple, Khushboo Jindal, Beril Kiragasi, Siddharth Annaldasula, Ann Byrne, Lilly Chai, Mahdiar Sadeghi, Can Kayatekin, Srinivas Shankara, Katherine Wood Klinger, S. Pablo Sardi, Stephen L. Madden, Dinesh Kumar

The paper identifies a conserved SNCA co-expression module in human brain single-nucleus RNA-seq data and links it to Parkinson's Disease risk loci through protein-protein interaction networks and CRISPR validation.

bioRxiv · Jun 5, 2020 · PreprintNeuroscience