Author

Angela Simpson

Manchester Academic Health Science CentreORCID 0000-0003-2733-6666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Adnan ČustovićiD· 2 shared Amanda J. L. RidleyiD· 1 shared Andrew S. MacDonaldiD· 1 shared Annabel J. CurleiD· 1 shared Clare M. LloydiD· 1 shared Clare S MurrayiD· 1 shared Conal HaytoniD· 1 shared Craig LawlessiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersGenetic & Genomic Medicine

Adnan ČustovićORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintFeb 26, 2025

Hallmarks and metabolic regulation of type 2 activated human lung macrophages

Amanda J. L. Ridley, Annabel J. Curle, Stefano A. P. Colombo…·Andrew S. MacDonald

This study identifies hallmark gene expression and metabolic profiles of type 2 activated human lung macrophages using primary tissue-derived cells.

DOI 10.1101/2025.02.26.640352

humanbulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 21, 2024

SOX9-regulated matrix proteins predict poor outcomes in patients with COVID-19 and pulmonary fibrosis

Laurence Pearmain, Elliot J. Jokl, Kara Simpson…·Karen Piper Hanley

DOI 10.1101/2024.01.21.576509

humanproteomics

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Genetic & Genomic MedicineeLifePeer-reviewedMay 25, 2023

A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifies ANXA1 as a susceptibility locus for persistent wheezing

Raquel Granell, John A. Curtin, Sadia Haider…·on behalf of UNICORN and Breathing Together investigators

This study identifies ANXA1 as a susceptibility locus for persistent wheezing through a meta-analysis of GWAS data from UK birth cohorts.

30 citations

humanGWAS summary statistics

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Systems BiologybioRxivPreprintDec 20, 2017

Non-parametric mixture models identify trajectories of childhood immune development relevant to asthma and allergy

Howard H.F. Tang, Shu Mei Teo, Danielle C. M. Belgrave…·Michael Inouye

The paper identifies three distinct immune development trajectories in childhood using unsupervised clustering, revealing a high-risk atopic cluster associated with allergic diseases.

DOI 10.1101/237073

humanbulk RNA-seq

𝕏 PostBluesky