Τόμας Ζελένκα

This paper shows that reducing BCL11B in CD8+ T cells enhances anti-tumor response by preventing exhaustion and boosting stemness and cytotoxicity.

The paper identifies a novel SATB1 protein isoform with distinct biophysical properties and shows its role in T cell development and potential links to cancer.

BERLIN reanalyzes single-cell RNAseq data to identify cell types and lineages, showing accurate results in acute myeloid leukemia and tumor-reactive lymphocytes.

The paper identifies SATB1 as a tissue-specific genome organizer that regulates 3D enhancer networks in developing T cells, affecting immune system homeostasis and lineage specification.