Dorina Avram

This paper shows that reducing BCL11B in CD8+ T cells enhances anti-tumor response by preventing exhaustion and boosting stemness and cytotoxicity.

This study shows that methylmalonic acid impairs CD8+ T cell function and promotes tumor growth by inducing metabolic dysfunction and exhaustion.

BERLIN reanalyzes single-cell RNAseq data to identify cell types and lineages, showing accurate results in acute myeloid leukemia and tumor-reactive lymphocytes.