Yunsik Kang

Developmental and age-related synapse elimination is mediated by glial Croquemort

This study identifies glial Croquemort as a key regulator of synapse elimination during development and aging in Drosophila.

Structural basis of bulk lipid transfer by bridge-like lipid transfer protein LPD-3

This study determines the structure of the LPD-3 BLTP complex and reveals its mechanism for bulk lipid transfer through interactions with Intake and Spigot proteins.

Astrocyte growth during morphogenesis is driven by the Tre1/S1pr1 phospholipid-binding G protein-coupled receptor

The paper identifies Tre1 and S1pr1 as evolutionarily conserved regulators of astrocyte morphology through lipid signaling and competition for growth-promoting phospholipids.

Astrocyte-dependent local neurite pruning and Hox gene-mediated cell death in Beat-Va neurons

The paper identifies two neuronal subtypes in Drosophila that undergo distinct remodeling processes during metamorphosis, highlighting astrocyte-dependent pruning and Hox gene-mediated cell death.

Tweek-dependent formation of ER-PM contact sites enables astrocyte phagocytic function and remodeling of neurons

This study shows Tweek is essential for astrocyte phagocytosis and ER-PM contact formation during neuronal remodeling in Drosophila.

An ELISA-based method for rapid genetic screens in Drosophila

The paper develops a GFP-based ELISA assay for rapid, quantitative genetic screens in Drosophila, identifying Syntaxins as novel regulators of astrocyte-mediated synapse elimination.