Francisco Javier Chichón

This study identifies how a single mutation in the Omicron variant of SARS-CoV-2's ORF3a protein alters its host-cell remodelling effects, shifting from lipid accumulation to preserving Golgi structure.

This study presents the high-resolution cryo-EM structure of integrin αIIbβ3 bound to an anti-HPA-1a antibody, revealing how it blocks integrin activation and platelet aggregation.