Author

Yang Du

Uniformed Services University of the Health SciencesORCID 0000-0003-2773-1113Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yang Du1 paper · Valley City State University

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Yufen Han· 2 shared Abhinav DeoliD· 1 shared Amro AboukameeliD· 1 shared Asfar Sohail AzmiiD· 1 shared Bjorg GudmundsdottiriD· 1 shared Francis BurrowsiD· 1 shared Jaroslaw Pawel MaciejewskiiD· 1 shared Jay YangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Yufen Han

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 13, 2026

Combined Menin and XPO1 inhibition drive synergistic antileukemic activity in KMT2Ar and NPM1-m AML

Md. Hafiz Uddin, Sandhya Dhiman, Yufen Han…·Suresh Kumar Balasubramanian

This study shows that combining Menin and XPO1 inhibitors synergistically inhibits KMT2A-r and NPM1-m AML cell growth and improves survival in xenograft models.

DOI 10.64898/2026.03.10.710924

humanbulk RNA-seq

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Developmental BiologybioRxivPreprintMar 24, 2025

MLL1 complex is a critical regulator of fetal hemoglobin repression

Yufen Han, Bjorg Gudmundsdottir, Kristbjorn O. Gudmundsson…·Yang Du

This study identifies the MLL1 complex as a regulator of fetal hemoglobin repression and shows that targeting MEN1 or KMT2A increases fetal hemoglobin expression in erythroid cells.

DOI 10.1101/2025.03.24.645036

humanbulk RNA-seq

𝕏 PostBluesky