Dominic Furniss

Analysis of hand OA cartilage stratified by ALDH1A2 polymorphic variants reveals a targetable, anti-inflammatory role for retinoic acid in OA.

The paper identifies DIRC3-IGFBP5 as a shared genetic risk locus for trigger finger and carpal tunnel syndrome, linking IGF-1 signaling to both diseases.

This study identifies 49 genetic signals associated with varicose veins through a large GWAS and replication, highlighting potential therapeutic targets and biological pathways.

This study identifies 20 genetic loci associated with kidney stone disease, including novel variants in CYP24A1 and DGKD, which influence vitamin D metabolism and calcium-sensing receptor signaling.

This study identifies three new genetic loci associated with idiopathic pulmonary fibrosis and confirms 11 previously reported ones, highlighting mTOR signaling and mitotic spindle-assembly genes in disease susceptibility.

The paper identifies ADCYAP1 (PACAP) as a key molecule enhancing sensory neuron outgrowth in human nerve regeneration using carpal tunnel syndrome as a model.

This study identifies 43 tissue-specific gene associations with Dupuytrens disease risk and finds significant genetic correlations with BMI, type II diabetes, and lipid traits.

This study identifies genome-wide significant genetic loci for handedness and links them to microtubule-related genes associated with brain lateralization and neurodevelopmental disorders.