Valerija Dobričić

This study conducts GWAS on short tandem repeats (STRs) to identify novel genetic mechanisms in Alzheimer's disease using data from ~330,000 individuals.

This study finds that DunedinPACE, an epigenetic clock, most consistently associates with cognitive decline in older adults compared to other DNAm clocks and telomere length.

The paper identifies differentially expressed lncRNAs in Alzheimer's disease brains using RNA-seq data from multiple studies and brain regions.

The paper develops a multivariate methylation risk score using blood DNA methylation data to predict dementia risk and cognitive impairment in Alzheimer's and Parkinson's disease cohorts.

The paper maps DNA methylation quantitative trait loci (meQTL) in three tissues and uses Mendelian randomization to link DNAm to Alzheimer's and Parkinson's disease risk.

This study identifies four novel DNA methylation loci in the entorhinal cortex associated with Alzheimer's disease and finds significant epigenetic age acceleration in patients.

The paper correlates DNA methylation patterns between buccal and brain samples to identify CpG sites with significant methylation correlations and genetic determinants.

The paper assesses differential microRNA expression in Parkinson's and Alzheimer's disease brains, identifying shared miRNAs with potential pathogenic roles.

The paper identifies differentially expressed miRNAs in two brain regions of Alzheimer's patients using qPCR and RNA-seq, highlighting potential targets involved in AD pathogenesis.

This study performs GWAS on quantitative AD biomarkers and cognitive traits, identifying new loci associated with memory performance and cognitive decline.

The paper conducts GWAS on CSF Alzheimer's disease biomarkers, identifying genetic associations with NF-L, YKL-40, and Ng levels.

This study finds that worse self-reported sleep relates to faster hippocampal microstructural decline in β-amyloid positive adults, independent of genetic risk.

The paper conducts a genome-wide association study (GWAS) on Alzheimer’s disease CSF biomarkers in the EMIF-AD dataset, identifying novel genetic signals and confirming existing associations.

This study shows genetic risk for Alzheimer's disease affects hippocampal volume throughout life in a healthy population.

The paper examines the relationship between sleep problems and amyloid deposition in cortical regions with high HOMER1 expression in older adults, finding a stronger link in younger participants and regions with high HOMER1 expression.

This paper identifies differentially expressed microRNAs in Parkinson’s disease through meta-analyses of multiple datasets, finding significant associations in brain and blood samples.

This study identifies differentially expressed microRNAs in Alzheimer’s disease across brain, blood, and cerebrospinal fluid through a systematic review and meta-analysis of 147 datasets.

This study performs a systematic meta-analysis of genetic association studies in isolated dystonia, identifying significant signals in TOR1A, DRD1, and ARSG but finding no single variant with strong association.