Marion Silies

The paper shows how neural adaptation in fly olfactory neurons is compensated through circuit-level mechanisms to maintain background-invariant population codes.

This study identifies GABAergic feedback neurons C2 and C3 as critical for direction selectivity in Drosophila motion detection circuits.

The paper shows that temporal diversity in Drosophila visual circuits improves coding efficiency for natural motion by distributing encoding across complementary timescales.

The paper identifies how Drosophila visual circuits achieve stable contrast processing in natural scenes through spatially pooled luminance signals and divisive normalization.

The paper completes the list of cell types in the Drosophila optic lobe and identifies connectivity rules, revealing new families and clusters related to visual functions.

The paper identifies a regulatory logic in progenitors that generates functionally related neuronal subtypes, showing its conservation across species.

The paper identifies heterogeneous synaptic connectivity in Drosophila visual columns, showing Tm9 neurons have diverse inputs compared to uniform Tm1 and Tm2 neurons.

The paper shows that Drosophila uses circuitry beyond photoreceptors to achieve luminance-invariant vision across different timescales through bidirectional gain control.

This study identifies how GDAP1 loss of function disrupts actin signaling, leading to mitochondrial tubularity and metabolic changes in CMT4A.

The paper shows that first-order visual interneurons in Drosophila distribute contrast and luminance information across ON and OFF pathways to maintain stable behavior under changing illumination.

The paper shows that local direction-selective T4/T5 neurons in Drosophila encode optic flow fields for self-motion, forming a population code similar to vertebrates.

The paper shows how direction selectivity in the Drosophila OFF pathway is achieved through specific neuronal circuit elements and receptive field organization.

This study shows that m6A RNA methylation regulates RNAP II promoter-proximal pausing, affecting gene expression and transcription.

This study identifies NECAB2's role in an endosomal pathway for mitochondrial stress response and repair in striatal synapses, linking its loss to synaptic loss and behavioral deficits.

TAF-ChIP enables high-quality ChIP-Seq results from low cell numbers, matching conventional ChIP-Seq datasets in epigenetic profiles.

The paper shows that dFezf coordinates laminar-specific connectivity in Drosophila by both cell-intrinsic and cell-extrinsic mechanisms.