Helge Müller‐Fielitz

This study shows that Gαq/11 signaling in brain endothelial cells prevents endothelial dysfunction and cognitive decline in aged mice by maintaining vascular reactivity and preventing blood-brain barrier disruption.

This study shows that tanycytic cilia sense metabolic cues in the cerebrospinal fluid, affecting energy balance and metabolism in mice.

This study shows that TR{beta}-KO mice exhibit partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy when studied at thermoneutrality.

The paper investigates SARS-CoV-2 infection in the hypothalamus and associated regions, showing viral entry receptors and susceptibility factors linked to neurological symptoms in COVID-19.

This study demonstrates that gene therapy targeting brain endothelial cells improves neurological symptoms in a mouse model of MCT8 deficiency by increasing brain T3 levels and motor function.