Jens Mittag

The paper investigates how maternal thyroid hormone exposure affects DNA methylation at a leptin upstream enhancer in adipose tissue, with sex-specific impacts on body fat percentage.

This study investigates how THRB affects diurnal hepatic lipid metabolism in adult male mice, finding THRB deficiency disrupts metabolic rhythms and promotes steatosis.

This study shows that thyroid hormone-induced cardiac hypertrophy relies on noncanonical TR action, while heart rate regulation depends on canonical TR action, with TRβ compensating for TR absence.

This study shows that TR{beta}-KO mice exhibit partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy when studied at thermoneutrality.

This study shows that thyroid hormone levels do not significantly affect cardiac recovery in old mice with preexisting pressure-induced cardiac damage.

This study demonstrates that gene therapy targeting brain endothelial cells improves neurological symptoms in a mouse model of MCT8 deficiency by increasing brain T3 levels and motor function.

This study shows that high mitochondrial heteroplasmy in mice reduces lifespan and impairs glucose metabolism.