Lars Bräutigam

The paper demonstrates that sulanemadlin, a stapled peptide inhibitor of MDM2, specifically activates p53 in zebrafish without inducing apoptosis, enabling direct in vivo studies of p53 regulation.

This study tracks DNA-origami nanostructures in zebrafish embryos using imaging and single-cell RNA sequencing to understand their biodistribution and clearance mechanisms.

This paper develops a zebrafish model for medulloblastoma drug testing, showing that neural stem cell culture conditions enhance tumor cell homing and aggressiveness, enabling high-throughput screening.