Margareta Wilhelm

The paper shows JAML expression on NK cells is regulated by tumor microenvironment and MHC class I interaction, with implications for NK cell-mediated tumor killing.

This study shows ALK R1275Q mutation sustains an immature SCP-like cell state during sympathoadrenal commitment, increasing susceptibility to MYCN-driven neuroblastoma initiation.

This study shows that combining palbociclib and crizotinib enhances senescence and immune recognition in melanoma cells regardless of BRAF/NRAS status, reducing tumor growth.

This study shows that γδT cells can selectively kill medulloblastoma cells without harming neurons or stem cells, offering a safer and more effective treatment option.

This paper develops a zebrafish model for medulloblastoma drug testing, showing that neural stem cell culture conditions enhance tumor cell homing and aggressiveness, enabling high-throughput screening.