Author

Deborah Christen

RWTH Aachen UniversityORCID 0000-0003-2839-5983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Alessia PiergentiliiD· 1 shared Anne Kaiser· 1 shared Axel ChoidasiD· 1 shared Bert KlebliD· 1 shared Giulia RossettiiD· 1 shared Heidi E. GreulichiD· 1 shared Hubert SchorleiD· 1 shared Ivan G. CostaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alessia PiergentiliORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 18, 2026

PDE3A-SLFN12 Molecular Glues Target Multiple KIT D816V Cell Types in Preclinical Models of Mast Cell Malignancies

Xuhuang Fu, Anne Kaiser, Payal Chawla…·Martin Zenke

This paper identifies PDE3A-SLFN12 molecular glues as a novel therapeutic target for KIT D816V-driven mast cell malignancies, showing their efficacy in killing multiple KIT D816V cell types and synergy with tyrosine kinase inhibitors.

DOI 10.64898/2026.08.13.744624

humanproteomics

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