Author

Brendan Townsend

The University of QueenslandORCID 0000-0003-2839-8981Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

Julia K. PaganiD· 2 shared Alexis Bonfim‐MeloiD· 1 shared Anne HahniD· 1 shared Arnaud AhieriD· 1 shared Arnaud GaudiniD· 1 shared Ayenachew Bezawork‐GeletaiD· 1 shared Brett M. CollinsiD· 1 shared Chuan-Yang DaiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Julia K. PaganORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 27, 2026

Germline mitophagy selectively eliminates deleterious mitochondrial DNA across generations

Arnaud Ahier, Tessa Onraet, Daniel Campbell…·Steven Zuryn

This study shows that germline mitophagy selectively removes mutant mitochondrial DNA in C. elegans, reducing their transmission to offspring across generations.

DOI 10.64898/2026.06.24.734151

C. elegansDNA methylation

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Cell BiologyEMBO ReportsPeer-reviewedJul 11, 2024

PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4

Giang Nguyen, Brendan Townsend, Prajakta Gosavi…·Julia K. Pagan

This study identifies PPTC7 as a cofactor for SCFFBXL4-mediated degradation of BNIP3 and NIX, suppressing mitophagy and revealing a feedback mechanism to regulate mitochondrial homeostasis.

34 citationstop 3%

humanproteomics

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