Christy Luong

The paper identifies enhancer-like elements on ecDNA in colorectal cancer that are derived from transposable elements and are functionally active in cancer cell fitness.

This study shows Xist RNA modulates X-chromosome inactivation beyond early development, reversibly silencing escapee genes and altering topological domain structures in mouse embryos.

The paper shows how DNA motifs guide transcription factor cooperativity in embryonic face and limb mesenchyme, shaping cell identity and morphology.

The paper uses a single-cell multiome atlas of the human retina and deep learning to identify causal noncoding variants in eye diseases.