Seungsoo Kim

The paper uses transfer learning to predict how TF dosage affects chromatin accessibility, finding that motif affinity and distribution determine sensitivity or buffering of TF concentration changes.

The paper shows how DNA motifs guide transcription factor cooperativity in embryonic face and limb mesenchyme, shaping cell identity and morphology.

The paper modulates SOX9 levels in human facial progenitors to study dosage sensitivity and identifies regulatory elements and genes that are sensitive to SOX9 changes.

The paper introduces a new assay, MAP-C, to study chromosomal contacts and identifies three transcription factors that mediate inducible interchromosomal pairing in yeast.

This study identifies condensin-mediated chromatin condensation as a mechanism repressing transcription during quiescence in yeast and human cells.

This study examines the 3D genome organization in diploid yeast, finding dynamic homolog proximity and environment-induced gene relocalization.