Author

Sophia Rits‐Volloch

Boston Children's HospitalORCID 0000-0003-2910-1422Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Bing CheniD· 1 shared Bjorn Reino OlseniD· 1 shared G. M. Jonaid· 1 shared Haisun ZhuiD· 1 shared Hanqin PengiD· 1 shared Jacob AlleniD· 1 shared Jianming LuiD· 1 shared Md. Golam KibriaiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Bing ChenORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedNov 27, 2025

Effect of the S2' site cleavage on SARS-CoV-2 spike

Wei Kang Shi, G. M. Jonaid, Md. Golam Kibria…·Bing Chen

The paper reports a cryo-EM structure of the S2 fragment of SARS-CoV-2 after S2 cleavage, showing it represents a late fusion intermediate, and shows that S2 cleavage accelerates membrane fusion.

10 citationstop 2%

cryo-EMexperimental assay

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Molecular BiologyAnnals of Integrative Molecular MedicinePeer-reviewedMar 13, 2019

RNA-DEPENDENT AMPLIFICATION OF MAMMALIAN mRNA ENCODING EXTRACELLULAR MATRIX COMPONENTS: IDENTIFICATION OF CHIMERIC RNA INTERMEDIATES FOR alpha1, beta1, AND gamma1 CHAINS OF LAMININ.

Vladimir Volloch, Sophia Rits‐Volloch, Bjorn Reino Olsen

The paper identifies chimeric RNA intermediates in laminin mRNA from EHS mouse tumor cells using next-generation sequencing.

18 citations

mousebulk RNA-seq

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