Author

Long Nguyen

Princeton UniversityORCID 0000-0002-3347-438XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Long Nguyen2 papers · La Trobe University

Biology Disciplines

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Bioengineering· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Allan J.W. LuiiD· 1 shared Cai Zhou· 1 shared Cameron MyhrvoldiD· 1 shared Carlos CaldasiD· 1 shared Chih-chieh Yu· 1 shared Daniel Guerrero-RomeroiD· 1 shared Daniel J. CoheniD· 1 shared Federico GaitiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

Allan J.W. LuiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Protein Deimmunization with a Generative Diffusion Model

Zijie Chen, Chih-chieh Yu, Cai Zhou, Xinyun Jiang, Long Nguyen, Cameron Myhrvold, Tommi S Jaakkola, Kaiyi Jiang

The paper introduces MESSI, a generative diffusion model for deimmunizing proteins by designing sequences with minimal immunogenicity while preserving structure and function.

bioRxiv · Oct 16, 2026 · PreprintBioengineering

Chemotherapy reshapes cellular clonal landscape via persister programs in breast cancer xenografts

Sarah Kronheim, J C M Wang, Jiao Yi Chen, Daniel Guerrero-Romero, Suet‐Feung Chin, Giulia Lerda, Allan J.W. Lui, Oscar M. Rueda, Federico Gaiti, Carlos Caldas, Long V. Nguyen

This study shows chemotherapy reshapes clonal architecture in breast cancer xenografts by selecting for chemotherapy-resistant clones and stress response programs.

bioRxiv · Apr 6, 2026 · PreprintCancer Biology

Large-scale control over collective cell migration using light-controlled epidermal growth factor receptors

Kevin Suh, Richard H. Thornton, Long Nguyen, Payam E. Farahani, Daniel J. Cohen, Jared E. Toettcher

This study uses light-controlled EGF receptors to precisely manipulate tissue movements in epithelial cells, showing light can drive millimeter-scale rearrangements.

Cell Systems · Mar 1, 2025Peer-reviewedBioengineering