David Anthony Seminowicz

The paper demonstrates that TMS-induced pupil dilations are a valid cortical excitability proxy, with larger pupil size indicating higher excitability, supported by Bayesian evidence across three experiments.

The paper investigates sex-dependent changes in insular cortex connectivity in a rat model of comorbid pain, finding increased insular-thalamo connectivity in female rats.

The paper develops a transient marmoset model of myofascial temporomandibular disorder using nerve growth factor injections, showing mechanical hypersensitivity and circadian changes without jaw dysfunction.

This study examines claustrum activation during four cognitive tasks using fMRI, finding bilateral activation during cognitive control phases and supporting the NICC model.

This study investigates the thermal grill illusion (TGI) and finds it elicits primary hyperalgesia in males and secondary hyperalgesia in all participants, suggesting spinal dorsal horn integration and involvement of HPC neurons.

This study investigates whether rTMS affects peak alpha frequency (PAF) and pain in response to NGF-induced muscle pain, finding no significant change in PAF but suggesting PAF proximity to rTMS frequency may influence pain relief.

This study identifies the claustrum as a key initiator of task-dependent network states in cognitive control using fMRI and structural connectivity analyses.

The paper examines resting state functional connectivity of the marmoset claustrum using fMRI data, finding connections to multiple brain regions similar to human and rodent studies.

This study shows that PSI-rTMS reduces tonic pain and pain-related cortical inhibition in humans, with changes in TEP N45 peak levels mediating the analgesic effect.

This study examines how prolonged elbow pain and rTMS affect cortical inhibition using TMS-EEG, finding that pain severity correlates with increased N45 peak and rTMS reduces it.

This study shows that the analgesic effect of rPMS in acute pain is due to its auditory component, not peripheral nerve stimulation.

This study shows that 5 days of rTMS before pain onset reduces future pain intensity and functional impairment, without mediation by corticomotor excitability or sensorimotor peak alpha frequency.

This paper reviews non-invasive brain stimulation effects on peak alpha frequency, finding limited and inconsistent evidence of modulation.

This paper investigates the correlation between phosphene and motor transcranial magnetic stimulation thresholds using meta-analysis, finding a moderate correlation and methodological influences.

The paper identifies pathological claustrum activity and its influence on cognitive network processing in chronic pain patients.

This study examines how nicotine affects pain sensitivity and whether changes in peak alpha frequency mediate these effects, finding small pain reductions with nicotine but no mediation by PAF changes.

This study uses combined TMS-EEG to show that experimental pain increases the amplitude of the N45 TEP peak, suggesting a role for GABAergic neurotransmission in pain perception.

This study characterizes pain, functional impairment, and hyperalgesia from NGF injections in a TMD model, revealing sex differences in pain experience.

The paper identifies synaptic connections from the claustrum to multiple cortical regions, supporting network motifs involved in cognitive control.

The paper identifies three dimensions linking migraine symptoms to brain functional connectivity using CCA and RSFC, revealing novel network targets and patient subtypes.

This study investigates how somatosensory and auditory evoked potentials affect TMS-EEG recordings and finds that sensory contamination in TEPs is non-linear and significant beyond 70ms post-stimulation.

This study shows that tonic pain in healthy humans alters functional connectivity within the Descending Pain Modulatory Network, with specific connections predicting pain intensity and being modulated by pain.

This study shows prolonged pain slows peak alpha frequency by reducing fast alpha power, suggesting a potential therapeutic target for pain management.

The paper investigates whether resting alpha frequency is a reliable biomarker for predicting sensitivity to prolonged pain in healthy individuals.

This study identifies 6-9 Hz cortical oscillations as a reliable biomarker for detecting chronic pain in rats by comparing individual pre-injury baselines to post-injury power changes.

The paper investigates how prolonged tonic pain affects intrinsic brain networks in healthy humans, finding altered functional connectivity in pain modulation networks.

This study finds that mTBI patients with post-traumatic headache have reduced grey matter volume in specific brain regions compared to those without headache and healthy controls.

This study uses fMRI to show the claustrum is functionally connected to cognitive networks and activates during cognitive tasks, independent of sensorimotor processing.

The paper links slow peak alpha frequency and corticomotor depression to increased pain susceptibility in a transitional pain model.