Author

Daoyi Li

Purdue University West LafayetteORCID 0000-0003-2913-8049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Wen JiangiD· 3 shared Xiaoqi ZhangiD· 2 shared Anllely FernándeziD· 1 shared Bernardino Francesco GhettiiD· 1 shared Chen Qi· 1 shared Fei SuniD· 1 shared Frank S. VagoiD· 1 shared Grace I. HallinaniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

Wen JiangORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

cryoAgent: An agentic workflow for robust and adaptive end-to-end cryo-EM image processing

Daoyi Li, 杨少迪, Taining Pei, Chen Qi, 肖茜, Tongxin Niu, Yan Zhang, Yun Zhu, Fei Sun

cryoAgent improves cryo-EM image processing by enabling autonomous, adaptive workflows that enhance reconstruction quality and identify new structural states.

bioRxiv · Sep 29, 2026 · PreprintBiophysics

Helicon: Helical indexing and 3D reconstruction from one image

Daoyi Li, Xiaoqi Zhang, Wen Jiang

Helicon enables helical indexing and 3D reconstruction from a single 2D image using linear regression and regularization techniques.

Journal of Structural Biology · Oct 21, 2025Peer-reviewedBiophysics

Validation of helical symmetry parameters in EMDB

Daoyi Li, Maité Pérez, Xiaoqi Zhang, Jiaqing Li, Wen Jiang

The paper validates helical symmetry parameters in EMDB by identifying and correcting inconsistencies between parameters and density maps.

Acta Crystallographica Section D Structural Biology · Aug 21, 2025Peer-reviewedBiophysics

Cross-β helical filaments of Tau and TMEM106B in Gray and White Matter of Multiple System Tauopathy with presenile Dementia

Md Rejaul Hoq, S.R. Bharath, Grace I. Hallinan, Anllely Fernández, Frank S. Vago, Kadir A. Ozcan, Daoyi Li, Holly J. Garringer, Rubén Vidal, Bernardino Francesco Ghetti, Wen Jiang

The paper determines that tau and TMEM106B filaments from gray and white matter in MSTD have identical folds.

Acta Neuropathologica · Mar 23, 2023Peer-reviewedNeuroscience