Jennifer S. Kim

This study shows that female sex and APOEe4 genotype differentially affect microglial transcriptomic profiles in the hippocampus and cortex of mice.

The paper integrates microglia morphology and gene expression using spatial transcriptomics and proteogenomics to identify morphology-related genes in the human brain.

This study shows that repeated LPS exposure induces training and tolerance in microglial responses across brain regions, with distinct gene expression patterns and morphological changes.

The paper develops an open-source pipeline to characterize microglia morphology at single-cell resolution using ImageJ and R, identifying distinct morphological states across brain regions and conditions.

This study reveals novel extracellular matrix (ECM) structures around excitatory neurons using HaloTag-HAPLN1, showing spatial and temporal regulation of ECM deposition and heterogeneity among neuronal populations.

This study shows that inhibiting Hdac3 enhances microglial neuroprotective functions and gene expression responses to inflammation.

This paper introduces a method called 3D-seq to map DNA-protein interaction sites in vivo using a modified cytosine deaminase, demonstrating its application in Pseudomonas aeruginosa transcription factors.