Lena Feige

This study shows that the K-D-K-E motif in RABV L protein's methyltransferase domain is crucial for immune evasion by altering viral and host RNA methylation, increasing sensitivity to interferon, and reducing pathogenicity.

The paper investigates how rabies virus interacts with different human brain cell types, identifying a pro-viral astrocyte subpopulation that enhances viral transcription.