Author

Jos F.H.M. Brouwers

Avans University of Applied SciencesORCID 0000-0003-2924-3279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Boris MačekiD· 2 shared Daniela M. Vogt WeisenhorniD· 2 shared Gerard J.M. MartensiD· 2 shared Julia Catherine FitzgeraldiD· 2 shared Thomas GasseriD· 2 shared Ana GarciaiD· 1 shared Anna Schaedler· 1 shared Aslihan Ugun‐KlusekiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Boris MačekORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 27, 2025

PINK1 regulates cholesterol homeostasis via SCAP phosphorylation in human dopaminergic neurons

Karan Sharma, Claudia Cavarischia-Rega, Dina Ivanyuk…·Julia Catherine Fitzgerald

This study shows that PINK1 regulates cholesterol homeostasis in human dopaminergic neurons by phosphorylating SCAP, and restoring cholesterol levels rescues defects in neurotransmitter uptake.

DOI 10.1101/2025.08.27.672574

humanexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 22, 2019

PINK1 Regulates Dopamine and Lipids at Mitochondria to Maintain Synapses and Neuronal Function

Christine Bus, Sven Geisler, Marita Pauline Feldkaemper…·Julia Catherine Fitzgerald

This study identifies PINK1's role in regulating mitochondrial function, lipid metabolism, and dopamine homeostasis in dopaminergic neurons, showing that cholesterol depletion can reverse PINK1-related phenotypes.

3 citations

humanexperimental assay

𝕏 PostBluesky