Gerard J.M. Martens

This study shows that PINK1 regulates cholesterol homeostasis in human dopaminergic neurons by phosphorylating SCAP, and restoring cholesterol levels rescues defects in neurotransmitter uptake.

This study shows that somatosensory experience in adult rats alters white matter structure and myelin-related gene expression, suggesting myelination as an underlying mechanism.

This study identifies PINK1's role in regulating mitochondrial function, lipid metabolism, and dopamine homeostasis in dopaminergic neurons, showing that cholesterol depletion can reverse PINK1-related phenotypes.

This study shows cocaine increases extracellular dopamine and serotonin by depleting storage vesicles in the rat nucleus accumbens, with individual differences in vesicular release affecting behavior and drug intake.

This study shows that disrupting the ANK3 gene in mice affects microtubule dynamics via GSK3/CRMP2 signaling, linking it to psychiatric illness mechanisms.