Author

Dina Ivanyuk

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Maria Jose Perez J.iD· 2 shared Michela DeleidiiD· 2 shared Thomas GasseriD· 2 shared Vasiliki PanagiotakopoulouiD· 2 shared Aleksandra ArsićiD· 1 shared Boris MačekiD· 1 shared Carlo Fiore ViscomiiD· 1 shared Christine Fröhlich· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Maria Jose Perez J.ORCID

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3 papers

Recent·Most cited

PINK1 regulates cholesterol homeostasis via SCAP phosphorylation in human dopaminergic neurons

Karan Sharma, Claudia Cavarischia-Rega, Dina Ivanyuk, Christine Fröhlich, Jos F.H.M. Brouwers, Gerard J.M. Martens, Philip Seibler, Javier Jarazo, Thomas Gasser, Daniela M. Vogt Weisenhorn, Boris Maček, Julia Catherine Fitzgerald

This study shows that PINK1 regulates cholesterol homeostasis in human dopaminergic neurons by phosphorylating SCAP, and restoring cholesterol levels rescues defects in neurotransmitter uptake.

bioRxiv · Aug 27, 2025 · PreprintNeuroscience

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

Maria Jose Perez J., Dina Ivanyuk, Vasiliki Panagiotakopoulou, Gabriele Di Napoli, Stefanie Kalb, Dario Brunetti, Rawaa Al‐Shaana, Stephan A. Kaeser, Sabine A. K. Fraschka, Mathias Jucker, Massimo Zeviani, Carlo Fiore Viscomi, Michela Deleidi

This study shows that PITRM1 deficiency in human cerebral organoids leads to Alzheimer's-like pathology, including protein aggregates and tau pathology, while 2D cultures do not show these features.

Molecular Psychiatry · Jul 6, 2020Peer-reviewedNeuroscience

Interferon-γ signaling synergizes with LRRK2 in human neurons and microglia

Silvia De Cicco, Dina Ivanyuk, Wadood Haq, Vasiliki Panagiotakopoulou, Aleksandra Arsić, David C. Schöndorf, Cong Yu, Maria Jose Perez J., Ruggiero Pio Cassatella, Meike Jakobi, Nicole Schneiderhan‐Marra, Ivana Nikić, Thomas Gasser, Michela Deleidi

This study shows that IFN-γ and LRRK2 synergize in human neurons and microglia, leading to defects in neurite elongation and microglial activation.

bioRxiv · Jan 30, 2020 · PreprintNeuroscience