Processivity and BDNF-dependent modulation of signalling endosome axonal transport are impaired in aged mice
David Villarroel‐Campos, Elena R. Rhymes, Andrew Paul Tosolini…·James N. Sleigh
The paper investigates how aging affects signaling endosome transport in motor axons and finds that processivity is impaired, which is not rescued by BDNF treatment due to reduced TrkB receptor expression.