Author

Jacob T. Beckley

SiteOne Therapeutics (United States)ORCID 0000-0003-2950-6462Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:non-human primate· 1

Frequent Co-Authors

Anton Delwig· 1 shared Bryan D. MoyeriD· 1 shared David C. YeomansiD· 1 shared Dennis MonteleoneiD· 1 shared George Luu· 1 shared Hassan Pajouhesh· 1 shared Holly S. HajareiD· 1 shared J. Du BoisiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anton Delwig

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1 paper

Recent·Most cited

NeuroscienceScientific ReportsPeer-reviewedSep 9, 2020

Discovery of a Selective, State-Independent Inhibitor of NaV1.7 by Modification of Guanidinium Toxins

Hassan Pajouhesh, Jacob T. Beckley, Anton Delwig…·John V. Mulcahy

This paper describes the discovery of ST-2262, a selective NaV1.7 inhibitor with state-independent action, showing reduced pain sensitivity in non-human primates.

41 citations

non-human primateexperimental assay

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