Brian E. Vestal

Comparative Evaluation of DDA and DIA Based Proteomic Workflows in Beryllium Related Lung Disease

This study compares DDA-MS and DIA-MS for proteomic analysis of lung compartments in beryllium-related disease, finding DIA-MS provides better quantitative completeness and detects more low-abundance proteins.

Differential Expression Analysis for Longitudinal Single-Cell RNA-Sequencing Studies Using REBEL

The paper introduces REBEL, a method for analyzing differential expression in longitudinal scRNA-seq data, showing it controls false discovery rate and has competitive power.

Monocyte Subset Predict Clinical Outcomes in Fibrotic Hypersensitivity Pneumonitis

The paper identifies monocyte subsets associated with clinical outcomes in fibrotic hypersensitivity pneumonitis using single-cell RNA sequencing.

Siglec-F Deficiency Prevents Fibrosis After Bleomycin-Induced Acute Lung Injury

This study shows that Siglec-F deficiency reduces fibrosis in bleomycin-induced lung injury by altering gene expression in airspace macrophages.

Antennal RNAseq reveals odorant receptors with sex-biased expression in the common eastern firefly, Photinus pyralis

The paper identifies sex-biased odorant receptor expression in the common eastern firefly, suggesting a role in mating signals despite its reliance on visual flashing.

Simulating Longitudinal Single-cell RNA Sequencing Data with RESCUE

The paper introduces RESCUE, a method to simulate longitudinal scRNA-seq data, incorporating between-sample and between-subject variability, and demonstrates its use in study planning.