Author

Mirjana Carli

Mario Negri Institute for Pharmacological ResearchORCID 0000-0003-2978-3849Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

Adriano ChiòiD· 1 shared Alice MigazziiD· 1 shared Andrea CalvoiD· 1 shared Bryan J. TraynoriD· 1 shared Claudia VillaniiD· 1 shared Cristina MogliaiD· 1 shared Edoardo MicottiiD· 1 shared Eliana Sammali· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Adriano ChiòORCID

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2 papers

Recent·Most cited

NeuroscienceBrainPeer-reviewedSep 14, 2021

Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia

Laura Pasetto, Maurizio Grassano, Silvia Pozzi…·Valentina Bonetto

This study shows that defective cyclophilin A (PPIA) leads to TDP-43 proteinopathy, contributing to ALS and FTD by disrupting TDP-43 function and causing neurodegeneration.

32 citations

mouseprotein structure

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NeuroscienceNeuropharmacologyPeer-reviewedJul 8, 2020

Fluoxetine rescues rotarod motor deficits in Mecp2 heterozygous mouse model of Rett syndrome via brain serotonin

Claudia Villani, G. Sacchetti, Mirjana Carli, Roberto William Invernizzi

This study shows fluoxetine improves motor coordination in Mecp2 heterozygous mice by increasing brain serotonin levels, suggesting serotonin-enhancing drugs may help RTT motor symptoms.

17 citations

mouseexperimental assay

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